Gamma-enolase: a well-known tumour marker, with a less-known role in cancer

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Gamma-enolase: a well-known tumour marker, with a less-known role in cancer

BACKGROUND Gamma-enolase, known also as neuron-specific enolase (NSE), is an enzyme of the glycolytic pathway, which is expressed predominantly in neurons and cells of the neuroendocrine system. As a tumour marker it is used in diagnosis and prognosis of cancer; however, the mechanisms enrolling it in malignant progression remain elusive. As a cytoplasmic enzyme gamma-enolase is involved in inc...

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ژورنال

عنوان ژورنال: Radiology and Oncology

سال: 2015

ISSN: 1581-3207

DOI: 10.1515/raon-2015-0035